0.75 CME. This course is intended to help clinicians be aware of the mental health needs and risks in patients with Lyme disease and educates on appropriate professional mental health referral, based on symptoms and clinical presentation. This concise, data-driven overview will help clinicians quickly access the latest evidence on Lyme disease persistence after standard treatments, useful in overturning the long-held belief that Lyme disease is always easy to treat and cure.